Arginine is one of the 20 amino acids that make up proteins. It plays an essential role in many functions of the body, including cell division, healing of wounds, the formation of creatine, the elimination of ammonia, the proper functioning of the immune system and the secretion of certain hormones , such as growth hormone. Additionally, arginine is the precursor to nitric oxide (NO), a substance that promotes the dilation of blood vessels.

Arginine is generally considered a “semi-essential” amino acid because our bodies are capable of producing it in sufficient quantities under normal conditions. However, in certain situations, such as significant trauma, serious infection, or major surgery, arginine supplementation may be recommended.

Arginine has potential benefits in several areas:

Physical performance: Arginine is known to improve vascularization and muscle congestion. Its role in the formation of creatine can contribute to muscle development and proper functioning (Campbell et al., 2004).

Sexual dysfunction: By promoting the production of nitric oxide, arginine may help increase blood flow, which may be beneficial for treating erectile dysfunction in men and certain sexual dysfunctions in women by improving vaginal lubrication and sexual arousal (Chen et al., 1999; Stanislavov and Nikolova, 2003).

Additionally, studies have suggested that arginine may play a role in other areas, such as:

• Improved wound healing: Arginine can promote tissue regeneration and accelerate wound healing (Witte et al., 2002).
• Boosting immunity: Arginine may strengthen the immune system by supporting lymphocyte proliferation and immune cell function (Curis et al., 2005).

It is important to note that the effects of arginine may vary from person to person and additional studies are needed to confirm these potential benefits. It is recommended to consult a healthcare professional before starting any arginine supplementation.

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References :

• Campbell, B.I., La Bounty, P.M., Roberts, M. (2004). The ergogenic potential of arginine. Journal of the International Society of Sports Nutrition, 1(2), 35-38.
• Chen, J., Wollman, Y., Chernichovsky, T., Iaina, A., Sofer, M., & Matzkin, H. (1999). Effect of oral administration of high-dose nitric oxide donor L-arginine in men with organic erectile dysfunction: results of a double-blind, randomized, placebo-controlled study. BJU International, 83(3), 269-273.
• Stanislavov, R., & Nikolova, V. (2003). Treatment of erectile dysfunction with pycnogenol and L-arginine. Journal of Sex & Marital Therapy, 29(3), 207-213.
• Witte, M.B., Barbul, A., Schick, M.A., Vogt, N., Becker, H.D., & Rabinovici, R. (2002). L-arginine supplementation enhances diabetic wound healing: involvement of the nitric oxide synthase and arginase pathways. Metabolism, 51(10), 1269-1273.
• Curis, E., Nicolis, I., Moinard, C., Osowska, S., Zerrouk, N., Bénazeth, S., … & Cynober, L. (2005). Almost all about citrulline in mammals. Amino acids, 29(3), 177-205.